In experiments on male Wistar rats by means of transbronchial electroplethysmography and catheterization of the pulmonary artery, changes in hemodynamics of the small circle were traced in response to a change in body position relative to the gravity vector in male Wistar rats when adapting to high altitude conditions for 60 and 150 days. Served as control similar experiments on the plain. It is shown that the gravitational redistribution of blood filling and blood flow in the lungs in the mountains is less pronounced than in the plain. This is due to an increase in the rigidity of the arterial vascular bed of the lungs and, accordingly, an increase in the reactive component of hydraulic resistance. The pressure response in the pulmonary artery at the moment of a change in body position was well expressed both on the plain and in the mountains. On the plains, the transition to the passive orthostatic position was accompanied by a decrease in both systolic and the percentage of, to a large extent, diastolic pressure, and the transition to the passive antiorthostatic position was accompanied by an increase in pressure in the pulmonary artery with approximately the same proportions of changes in systolic and diastolic. The results obtained are generally consistent with the concept of regional irregularity of blood circulation in the lungs, according to which the values of the gradient in blood filling and blood flow in the lungs are determined by the action of gravity and exists at any position of the body in space, although in a horizontal position (lying on the back) and on a plain, and in the mountains we did not find reliable gravitational differences in rats either in blood filling in blood flow.

In this article, mathematical modeling is considered, using the example of compartment models that were proposed in the 1920s by Kermak and McKendrick. In particular, the SIRS and SEIR-HCD models, which are basic for other more complex models, are given as an example. The features of these models are that they are based on a system of differential equations. The article lists both the advantages of these models and the disadvantages. As a result, we presented a system of equations.

In today’s modernized education system, it is important to provide students with a comprehensive education and teach them to apply the acquired knowledge in practice. The subject of geometry, taught in the school course, also contributes to the student’s knowledge of the world around him, the study of the properties of objects in space. The article discusses the features of one of the sections of geometry-stereometry, similarities and differences in the field of planimetry. The purpose and essence of teaching the field of stereometry in the school course are also indicated, as well as the benefits of stereometry for students are analyzed.

The article analyzes the features of the use of audio materials in teaching students speaking in a foreign language, the description of the introduction into practice of innovative technologies for teaching foreign languages, the specifics of using the audio methods in the classroom in the learning process. The purpose of the work is to determine the optimal conditions for teaching students speaking, as well as to show the ways of the most complete disclosure audio methods based on the development speaking. The article solves the problems of finding ways to implement conversational speech in a foreign language lesson; optimal directions for activating students' conversational skills when using the audio method. The scientific and practical significance of the article lies in its development and implementation of the pedagogical practice of teaching speaking. The paper presents didactic materials approved for the use of audio materials in teaching. An example of an audiovisual method exercise system based on the development of speaking is also given. The article focuses on the effectiveness of audio methods as a tool for improving language skills and abilities. The results of the study prove that audio materials provide an opportunity for deeper mastery of speaking while learning a foreign language.

The Kazakh language course conducted in higher educational institutions for russian groups has its own specific. There is a need for further development and independent improvement of the language skills acquired within the framework of the school blueprint. Achieving average-level, above-average results requires serious qualifications. Some of the optimal approaches to language acquisition have a positive impact on students. Creative adaptive learning is one of the manifestations of language literacy requisite by modern youth. It is characterized by the fact that, as a result of its consistency, purposefulness, it can have a direct impact on the quality of teaching the subject, clearly and accurately reflects the level of knowledge and skills of the student, optimizes the assessment, gives direction to determine the extant of shape of various competencies of the student and the development of his capabilities in the future. We can also motivate to perfect knowledge of the Kazakh language by systematically providing cognitive, educational, informational tasks as independent work. Such approaches are of great importance for acquisition the Kazakh language in the audience with other languages in the direction of educating students of the intelligence and mind, the culture of Kazakh thinking and speech, the formation of personal abilities.

Currently, an inclusive education system is organized in the process of adaptation of children with special educational needs to the environment. This process is very relevant in the world and in the country.

The main purpose of the article «interaction of family and school in inclusive education» is to establish close ties between parents raising a child with special educational needs and the staff of an educational secondary school, the organization of trusting and strong relationships with school teachers.

The main subject participating in the inclusive education system is the child, the school staff and the parent.

A parent is a person who occupies a special place in the education of a child with special educational needs, adaptation of the child to the environment. Psychological and pedagogical assistance to parents is organized by the school staff. The joint activity of specialists (teachers, psychologists, speech therapists, speech pathologists, social educators) has a huge impact on the development of the child.

When conducting correctional and developmental classes, parents receive personal information about their child, special consultations are given for parents. Parents should take an active part in the correctional and developmental activities of the child, conduct repeated classes outside of school hours (fixing the studied material at home, medical treatment).

About the sphere of use of the Kazakh language of the present time both in social networks and in public places. We can say that compared to previous years, we have achieved significant results over the past five or six years. After Independence, the role of the Kazakh language in the field of socio-economic, scientific, technical and general culture has increased, and the volume of use has expanded. The requirements for the study of the Kazakh language have increased, especially in other language groups of the university. In this regard, the knowledge of the Kazakh language by students of Russian groups is guided by the basics of modern education in the educational process. Listening to the Kazakh language, speaking, reading, writing, mastering high-quality knowledge and culture of the Kazakh language is a prestigious duty of Kazakhstanis. Along with international processes, the development-oriented education system also requires a new organization of all branches in order to study it from a different angle. Teaching true connoisseurs of the language, national historical and cultural traditions, who understand the role of the Kazakh language in the world community, is very important today. Only with the help of competent language learning, the future of the Kazakh people can be bright.

Any field of activity, within the framework of modern scientific and technical development, has undergone, and continues to make more and more adjustments to its structure. Changes in the structure of the sphere of education, in particular - the discipline "Physical culture", is no exception.

The main documentation on which the lessons on the subject are based is the educational-methodological complex of the discipline (EMCD), the working curriculum (WC), as well as their constituent parts.

In the current conditions (pandemic), education had, for the most part, to switch to such a type of education as distance learning. Physical education teachers, coaches and teachers had to find new methods and means of conducting classes.

Changing the methods (even coordinating ones) in conducting classes in the discipline "Physical culture" does not cancel its purposefulness. The goal - upbringing, development and maintenance of a healthy lifestyle among student youth, still remains relevant.

For effective investment activity of banks, it is necessary to optimize and manage the bank's securities portfolio.The modern portfolio management system has a sufficient arsenal of effective tools, including a number of principles and approaches.

The volatility of the Kazakhstan stock market requires the accounting service to pay increased attention to the main function of professional financial agents (including commercial banks) - resource management. The multi-dimensionality of the modern investment portfolio of a commercial bank goes beyond the traditional "accounting" model, that is, the description of the results of portfolio management activities by drawing up the balance sheet. Accordingly, within the framework of the organization of the subject of financial activity, the problem of managing the investment portfolio, building a model and technological implementation arises.

Given the huge potential of theoretical developments in the field of portfolio management, Kazakhstan's commercial banks are lagging behind in the practical implementation of management models. Decision-making within the standard organizational structure of commercial banks does not reflect the current capabilities and requirements for resource management. With the development of the Internet and information technologies in Kazakhstan, the time allocated to top managers for making managerial decisions has sharply decreased. Thus, it is necessary not only to develop a model of resource management in the financial markets, its practical implementation has also become a factor in the competitiveness of a commercial bank. The relevance of the study lies in the lack of a comprehensive approach to the practical implementation of the investment portfolio management process, starting with the creation of the organizational structure of a commercial bank and ending with the introduction of management models based on improved information.

The issues related to the contribution of schools of the Kostanay region to the defense of the country in 1941-1945 are considered. A special role is played by the activities of school students and teachers in their desire to help the front, despite the socio-economic difficulties during the Great Patriotic War.

The main potential in the state is the people. There are several ways to express dissatisfaction if people are unhappy. Unrest within the country is undoubtedly due to a misunderstanding of the policy of the ruling, due to positive rejection. Untimely resolution leads to various protests. The petitions that took place at the beginning of the twentieth century are one of the manifestations of this. This topic is studied from among historians, politicians, journalists, sociologists. But I haven't received the full price yet.

As early as the beginning of the 20th century, linguists noted the growing interest of writers in mythology, which prompted them to study this phenomenon in more detail. Although traces of mythology can be found throughout the history of world literature. After all, mythological motifs contributed to the creation of images, themes and plots known to the whole world. The mythological basis of a literary work is the highest level of intertextuality and the cultural immersion of the reader's imagination into the literary canvas of a work of art. Through the analysis of mythological images, additional authorial meanings and the ideological idea of any writer are revealed. I.S. Turgenev is very stingy in choosing emotionally colored vocabulary, but his vivid images, sometimes developing into symbols, are all the more valuable. "Poems in prose" have not been studied in the literary world from the point of view of mythotectonics, which determines the relevance of the study. The article deals with the images of Hercules, an old woman and a fly, which take their origins from ancient, Slavic and Eastern mythology.

The article discusses the role of key factors in the exchange rate formation of the Kazakhstani tenge. The study analyzes which factors are key for short-term and long-term forecasting. A linear regression model is built, with the STEP function on quarterly data from 01/01/2005 to 06/01/2021 using free statistical software with open source access and the R programming language. The STEP function allows you to choose the best model from one dependent and 14 independent variables. An analysis of domestic and foreign studies is carried out to identify the degree of relationship (positive or negative) between the key factors affecting the nominal exchange rate of the national currency of Kazakhstan. The relationship between the nominal exchange rate and direct or indirect state intervention is investigated. Access to data is a key issue for qualitative forecasting of the nominal exchange rate of the Kazakhstani tenge and affects the predictive power of the model. As recommendations, it is proposed to provide economic agents with KASE data. In conclusion, conclusions are drawn about the presence of objective prerequisites that impede the transition to a free-floating exchange rate in Kazakhstan.

The article examines the archetypal nature of labial consonants in the Turkic languages. In Turkology and Altaic studies, the correspondence of sounds is a well-studied problem. In the question of which of the labial consonants is an archetype, each scientist makes his own assumption. The purpose of this article is to generalize thoughts related to labial consonants and to link the development of labial consonants with speech ontogenesis.

From January 1, 2019, a special tax regime in the form of a tax on professional income began to operate on the territory of the Russian Federation. This scientific work is devoted to the study of the mechanism of implementation of this tax regime, its key theoretical and practical features, the analysis of this phenomenon based on foreign experience and the history of its origin. The Institute of "self-employment" in the last few years has been one of the key institutions of tax law, attention to which has been riveted both by scientists and citizens of the countries in which it began to operate. The author considers the stages of the legislative implementation of this institute on the territory of the Russian Federation, an assessment of the institute under study is carried out, in addition, a number of debatable issues are put up for discussion.

Mutagenic effect of physical factors and chemical substances (aziridine or ethylene imine, nitrosoethylurea, nitrosoethyleneurea) leads to increase of the spectrum of hereditary variability for breeding purposes, which however is not studied in full extent. Ecological study of anthropogenic factors action leading to disruption of certain links between chemical elements and their combinations, raise of heavy metals concentration in soil, facilitate examination of mutagenic and toxic properties of heavy metals. Increase in wheat yields by improving its genotype is one of the most urgent problems of agriculture and economy. At present, using traditional methods of selection and genetic studies, such as backcross selection, distant hybridization, and experimental mutagenesis, increased efficiency of obtaining genetically modified and improved forms of wheat [1-5]. Heavy metals are defined as metals having a density higher than 5 g/cm3. Of the total 90 naturally occurring elements divided into three classes by the degree of their threat, 53 are considered heavy metals and few are of biological importance. Accumulation of heavy metals such as cadmium (Cd) in the environment is now becoming a major cause of environmental pollution. Toxic metals can inactivate proteins, shifting metal cofactors, blocking active centers or causing allosteric changes. Besides, large number of those possesses ability of inducing mutagenic changes, tumors and causing macroscopic changes. Molecular mechanism of heavy metals toxicity is not completely understood. Cd is non-essential element that negatively affects plant growth and development, released into the environment by power stations, heating systems, metal working industries or urban traffic, which has high cumulative effect with almost no biodegradation. In plants it affects such processes as stomata opening, transpiration and photosynthesis, consequently chlorosis, leaf rolls and stunting are the main symptoms of Cd toxicity in plants accompanied by root browning, leaf red-brownish discoloration. It can also reduce the absorption of nitrate from root to shoot by inhibiting the nitrate reductase activity in shoots. The negative effect of Cd on plant growth was accompanied by an increase in dry to fresh mass ratio in all organs. Several researches have suggested that an oxidative stress could be involved in cadmium toxicity, by either inducing oxygen free radical production, or by decreasing enzymatic and non-enzymatic antioxidants [6-9]. On the other hand, the use of induced mutagenesis showed high efficiency in the production of forms with high yield, quality bakery, lodging resistance, modified plant height and resistance. And, this paper is an attempt of summarizing results performed by our group in this direction.

Animal husbandry has always been considered one of the main directions in the agricultural sector of Kazakhstan, being an integral element of the strategic food security of the state, providing employment and income generation for the population. One of the main indicators characterizing the well-being of the country is the consumption of livestock products per capita. Therefore, it is necessary to pay due attention to the qualitative development of agriculture, in particular the development of animal husbandry and increasing its efficiency.

Kazakhstan has great opportunities for the development of animal husbandry, this is due, first of all, to the country's natural competitive advantages, such as: favorable natural and climatic conditions, the availability of pastures, as well as the proximity of markets.

The purpose of the research was to optimize the main directions of development of animal husbandry in Kazakhstan using the benchmarking method. The processing of scientific and statistical material was carried out by the method of comparative analysis using benchmarking elements. The task of the research included the study of technical, economic and natural and climatic indicators characterizing the level of development of animal husbandry in the countries closest to Kazakhstan in terms of resource provision and climatic conditions. The article presents a comparative analysis of countries such as Mongolia and Canada, it should be noted that the selected objects of comparison are similar in terms of the specifics of the introduction of animal husbandry in Kazakhstan. Such an approach to solving the problem associated with the further development of animal husbandry based on benchmarking contains a certain element of novelty.

When calculating planned indicators, normative, calculation-analytical and optimization methods were used.

The features of the process of needle injection of raw meats with pickling brines are characterized. A multi-needle pneumatic brine injector with a pushing conveyor is described, as well as experiments on processing whole-muscle meat products with its help. The effect of the yield of pork loin, beef ham and pork neck upon the speed of the transporting rake was studied. The highest yield of loin was obtained at a feed rate of 0.012-0.0125 m/s, for ham – at 0.01-0.0115 m/s. The yield of the neck decreased with the decrease in the feed rate.

The introduction of modern high-quality, environmentally friendly materials, products and structures in the field of construction will significantly reduce the consumption of materials and energy consumption of construction facilities and significantly increase the productivity of the construction sector. One of the modern directions of construction is the production of first-class, resource-saving building materials, products and structures, as well as the design and construction of buildings that combine the convenience of planning solutions, environmental friendliness and energy efficiency.

There is an analysis of the mechanism of accidents and it shows that improving road conditions and improving the speed and braking properties of the car, stability and controllability does not increase the active safety of road traffic. These measures only move the boundaries within which the driver can drive safely. The parameters of quality of car operation, which characterize the traffic safety, have been determined. The values of car operation quality parameters that correspond to different levels of traffic safety have been defined. In order that the proposed parameters of quality of car operation can be used to control the safety of traffic modes by drivers and traffic police, the computer must be used to calculate these parameters as a standard residual of the car. The studies carried out made it possible to single out three indicators of the quality of driving a car, which characterize the safety of the driving mode: maximum speed is the ratio of the average speed to the maximum, called the speed coefficient, the standart deviation of the vehicle's longitudinal acceleration from the average value, which is called acceleration noise in the theory of traffic flows. The above indicators of the quality of driving are measured from the moment of the start of the trip.

The article clearly states the reasons for the active use of the Internet for the illicit trafficking of drugs, psychotropic substances and their analogues. Methods of selling drugs via the Internet are described, the principles of operation of online stores in general are shown.

The quality of sharpening of flat wood-cutting knives in a certain way affects the quality of the parts obtained. The sharpening process is carried out by a grinding carriage performing a rectilinear reciprocating motion relative to a fixed knife. When the massive carriage is reversed, free oscillations (transients) occur, which

leads to a violation of the straightness of the cutting edge of the knife, limited by the requirements of GOST. Reducing the vibration activity of the process and achieving the required quality of knife sharpening provides a constructive solution for reversing the movement, in which the reverse is performed by a lightweight node-a base table with a knife fixed to it, and a massive sharpening carriage is stationary.

The article considers aspects of the creation and development of automated process control systems. A comparative analysis of the main types of IS RD, as well as the peculiarities of their use are shown. Stages of development and further development of automatic control systems (ACS) were identified and considered. Devices of automated process control systems and integration of SCADA systems into the structure of ACS were studied. Existing challenges were identified and possible prospects for improvement and development were presented. It was concluded that the rational use of artificial intelligence to increase the efficiency of technological process automation.