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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">koz</journal-id><journal-title-group><journal-title xml:lang="ru">"Вестник Северо-Казахстанского университета имени Манаша Козыбаева"</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Manash Kozybayev North Kazakhstan University</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2958-003X</issn><issn pub-type="epub">2958-0048</issn><publisher><publisher-name>М. Қозыбаев атындағы СҚУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.54596/2958-0048-2024-3-9-14</article-id><article-id custom-type="elpub" pub-id-type="custom">koz-1727</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЕСТЕСТВЕННЫЕ НАУКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NATURAL SCIENCES</subject></subj-group></article-categories><title-group><article-title>Определение частоты встречаемости нейропатического компонента хронической онкологической боли</article-title><trans-title-group xml:lang="en"><trans-title>Determining the frequency of occurrence of the neuropathic component of chronic cancer pain</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амангелді</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Amangeldi</surname><given-names>A. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Караганда</p></bio><bio xml:lang="en"><p>Intern doctor, Karaganda Medical University.</p><p>Karaganda</p></bio><email xlink:type="simple">a-amangeldi@qmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колыбаева</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolybaeva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Караганда</p></bio><bio xml:lang="en"><p>Intern doctor, Karaganda Medical University.</p><p>Karaganda</p></bio><email xlink:type="simple">eldira.kolybayeva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НАО «Медицинский Университет Караганды»<country>Казахстан</country></aff><aff xml:lang="en">Karaganda Medical University NJC<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>20</day><month>09</month><year>2024</year></pub-date><volume>0</volume><issue>3 (63)</issue><fpage>9</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Амангелді А.Е., Колыбаева Э.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Амангелді А.Е., Колыбаева Э.А.</copyright-holder><copyright-holder xml:lang="en">Amangeldi A.Y., Kolybaeva E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.ku.edu.kz/jour/article/view/1727">https://vestnik.ku.edu.kz/jour/article/view/1727</self-uri><abstract><p>Оригинальное исследование было проведено с целью изучить распространенность и частоту встречаемости нейропатического компонента хронической боли у пациентов со злокачественными новообразованиями. Выборка когортного исследования была сформирована в КГП «Областной онкологический диспансер» г. Караганды. В исследовании были включены 374 онкологических пациентов. У 106 пациента была диагностирована нейропатическая хроническая боль разной степени интенсивности и локализации. Пациенты выборки была распределены методом конвертов на основную и контрольную группы. Каждая группа была детально проанализирована, описаны основные клинические характеристики у каждого пациента. Проанализированы пол, возраст, локализация и распространенность первичного очага злокачественного новообразования, вид проведенного противоопухолевого лечения.</p><p>В результате оригинального исследования выявлено, что нейропатический компонент хронической боли чаще встречается у женщины старше 50 лет. В подавляющем большинстве такие пациенты с диагнозом рак молочной железы III стадии, перенесших комплексное или комбинированное лечение. Учитывая выявленную когорту пациентов, у кого развивается хроническая нейропатическая боль, возможно раньше начать превентивные мероприятия. Данные меры позволят снизить бремя развития сложно купируемого вида хронической боли среди онкологических пациентов.</p></abstract><trans-abstract xml:lang="en"><p>The original study was conducted to study the prevalence and incidence of the neuropathic component of chronic pain in patients with malignant neoplasms. The cohort study sample was formed in the Regional Oncology Dispensary of Karaganda. The study included 374 cancer patients. Neuropathic chronic pain of varying intensity and localization was diagnosed in 106 patients. The sample patients were divided into the main and control groups using the envelope method. Each group was analyzed in detail, the main clinical characteristics of each patient were described. Gender, age, localization and prevalence of the primary focus of malignant neoplasm, and the type of antitumor treatment were analyzed.</p><p>The original study found that the neuropathic component of chronic pain is more common in women over 50 years of age. In the vast majority of cases, such patients are diagnosed with stage III breast cancer who have undergone complex or combined treatment. Given the identified cohort of patients who develop chronic neuropathic pain, it is possible to begin preventive measures earlier. These measures will reduce the burden of developing a difficult-to-treat type of chronic pain among cancer patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>боль</kwd><kwd>онкологическая боль</kwd><kwd>хроническая боль</kwd><kwd>нейропатическая боль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pain</kwd><kwd>cancer pain</kwd><kwd>chronic pain</kwd><kwd>neuropathic pain</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO global survey on the inclusion of cancer care in health-benefit packages, 2020-2021, Lion, France, 2024. - p.90.</mixed-citation><mixed-citation xml:lang="en">WHO global survey on the inclusion of cancer care in health-benefit packages, 2020-2021, Lion, France, 2024. - p.90.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">WHO guidelines for the pharmacological and radiotherapcutic management of cancer pain in adults and adolescents, Switzerland, 2018. - p.138.</mixed-citation><mixed-citation xml:lang="en">WHO guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents, Switzerland, 2018. - p.138.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Cancer Pain. 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